Vitamin E: inhibition of retinol-induced hemolysis and membrane-stabilizing behavior.

Vitamin-Induced Hemolysis

Case Summary A 47 year-old African American man presented to the hospital with three a day history of fever, shortness of breath, nausea, emesis, dark urine, and progressive confusion. The symptoms began one day following an infusion of a “vitamin complex” at his physician’s office. The patient’s medical history was significant for retroperitoneal fibrosis with multiple urological procedures, f...

Degradation of membrane phospholipids and thiols in peroxide hemolysis: studies in vitamin E deficiency.

Relationship between inhibition of membrane SH groups and hemolysis induced by SH inhibitors.

Many investigators have suggested that sulfhydryl (SH) groups may be essential for the maintenance of the integrity of mammalian erythrocytes (1-4). This conclusion was drawn after observing the hemolytic effects of such heavy metals as mercurials and such oxidants as oxygen or iodine on erythrocytes. In hemolytic anemia in man, a relationship between hemolysis and a deficiency of reduced gluta...

Vitamin E-Coated Polysulfone Membrane-Based Hemodiafiltration Attenuates Inflammation in a Rat Model of Lipopolysaccharide-Induced Systemic Inflammation

Background: Acute blood purification (ABP) therapy is used regularly in the clinical setting and reportedly alleviates organ failure associated with severe systemic inflammatory responses, leading to reduced mortality. The present study aimed to determine whether there is a difference in efficacy between polysulfone (PS) membranes, which are currently used regularly in the clinical setting, and...

The Efficacy of Vitamin E and Folic acid on the Acute Hemolysis Caused by Glucose-6 phosphate Dehydrogenase

Background: Glucose-6 phosphate dehydrogenase (G6PD) deficiency is the most common inherited enzyme deficiency of red blood cells involving the enzyme pathway of hexose monophosphate. This study was conducted to examine the effect of vitamin E and folic acid on the improvement of acute hemolysis caused by the G6PD deficiency in patients referred to 17 Shahrivar Hospital, Rasht. Materials and M...